PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Age-Dependent Directional Reversal of Total Testosterone Associations across the Phenome in NHANES 2011–2023

PPR ·

Human · Preprint

Abstract summarized · Quality not appraised
Studied
The researchers examined whether links between testosterone levels and disease change with age.
Who / model
The analysis used 21,847 adults in the NHANES survey, with measured testosterone levels.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
Found
Several disease associations differed across midlife age groups. Pooling ages could therefore hide opposing associations.
Limits
This examines hormone–disease associations in survey data. It does not establish the effects of testosterone treatment.

Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary

Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.21203/rs.3.rs-11002542/v1

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