SOURCE-LINKED STUDY SUMMARY
Aromatase inhibitors as endocrine modulators: from breast cancer therapy to male off-label use and doping practice.
Abstract summarizedQuality not appraised
- What was studied
- A review of aromatase inhibitors and their hormone, health and performance effects in men.
- Who / model studied
- Clinical and experimental research in male populations, including adolescent boys. The abstract gives no pooled sample size or follow-up duration.
- Studied dose & schedule
- Dose and schedule were not reported in the source used for this summary.
- What the study found
- Estrogen generally fell and testosterone rose, but responses varied. Testosterone increases tended to reverse after stopping and did not consistently improve sexual function, physical performance or reported well-being.
- Limitations & context
- Most studies did not systematically assess men previously exposed to anabolic steroids. Long-term effects of estrogen deprivation in adolescents remain uncertain.
Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1016/j.jsbmb.2026.107121