PEDEvidence@pedevidence

SOURCE-LINKED STUDY SUMMARY

The Impact of Common Medications on Male Fertility: An Updated Systematic Review.

Andrology ·

Review

Abstract summarizedQuality not appraised
What was studied
An updated systematic review of commonly used medicines and male reproductive outcomes.
Who / model studied
184 original studies published from 2016 to 2025, involving human males exposed to noncytotoxic medicines. Outcomes included sperm production, semen measurements and reproductive hormones.
Studied dose & schedule
Dose and schedule were not reported in the source used for this summary.
What the study found
The authors describe adverse hormone or fertility findings for medicines including testosterone, anabolic steroids and opioids, and highlight newer evidence involving drugs such as duloxetine, dutasteride and valproate.
Limitations & context
Findings were summarized descriptively across different drug classes. The abstract provides no drug-specific risk estimates, doses or reversibility data, so it cannot predict an individual's fertility outcome.

Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary

Review record & corrections

Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1111/andr.70381

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