The Impact of Common Medications on Male Fertility: An Updated Systematic Review.

Studied

An updated systematic review of commonly used medicines and male reproductive outcomes.

Who / model

184 original studies published from 2016 to 2025, involving human males exposed to noncytotoxic medicines. Outcomes included sperm production, semen measurements and reproductive hormones.

Studied dose & schedule

Dose and schedule have not yet been extracted for this summary.

Found

The authors describe adverse hormone or fertility findings for medicines including testosterone, anabolic steroids and opioids, and highlight newer evidence involving drugs such as duloxetine, dutasteride and valproate.

Limits

Findings were summarized descriptively across different drug classes. The abstract provides no drug-specific risk estimates, doses or reversibility data, so it cannot predict an individual's fertility outcome.

Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary