SOURCE-LINKED STUDY SUMMARY
Influence of the menstrual cycle and sex hormones on the response to genotoxic stress in human cells.
Abstract summarizedQuality not appraised
- What was studied
- Researchers tested how menstrual phase and sex hormones relate to cells' responses to DNA damage.
- Who / model studied
- Blood cells came from 10 naturally cycling women at three cycle phases and six age-matched men. Additional experiments used cell lines. Exposure duration is not stated.
- Studied dose & schedule
- Dose and schedule have not yet been extracted for this summary.
- What the study found
- Cells from the early follicular phase had the least DNA strand damage and highest survival after hydrogen peroxide. Cell death correlated with progesterone. Menstrual phase showed no clear effect on the measured DNA-repair signal or olaparib's inhibition.
- Limitations & context
- The authors describe this as a pilot and call for deeper investigation.
Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1016/j.toxlet.2026.113198