SOURCE-LINKED STUDY SUMMARY
Fall of the Titans: Anabolic-Androgenic Steroid Use in a Patient With a TTN Truncating Variant.
Abstract summarized · Quality not appraised
- Studied
- A case report described severe heart failure alongside nonprescription testosterone and aromatase-inhibitor use and an underlying genetic finding.
- Who / model
- One 35-year-old man with acute breathlessness reported use over the preceding year. No comparison group or follow-up duration is stated.
- Studied dose & schedule
- Dose and schedule have not yet been extracted for this summary.
- Found
- Heart imaging showed an ejection fraction of 25%. Genetic testing identified a pathogenic variant associated with the patient's dilated cardiomyopathy. This describes coexisting exposures and genetic susceptibility.
- Limits
- Study limitations were not stated in the abstract. Methodological quality has not been appraised.
Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary
Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1016/j.jaccas.2026.110248