SOURCE-LINKED STUDY SUMMARY
4-Phenylbutyric acid alleviates acrylamide-induced sexual behavioral deficits and testicular damage in male Wistar rats: modulation of ER-stress associated signaling.
Abstract summarizedQuality not appraised
- What was studied
- Whether 4-phenylbutyric acid reduced reproductive damage caused by acrylamide exposure in male rats.
- Who / model studied
- Thirty-two adult male rats were split into four groups of eight. Acrylamide was given for 28 days, with 4-phenylbutyric acid added during the final 14 days in two groups.
- Studied dose & schedule
- Dose and schedule have not yet been extracted for this summary.
- What the study found
- Acrylamide reduced sperm count and testosterone and damaged sexual behavior and testicular tissue. Treatment improved these measures and reduced markers related to cellular stress.
- Limitations & context
- This was an acrylamide-toxicity experiment in rats. It does not establish fertility, testosterone or sexual-performance benefits in healthy humans.
Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1007/s10735-026-10967-0