PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Gender Minority Stress, Testosterone, and Blood Pressure Responses to Stress in Transgender and Nonbinary Adults.

American journal of physiology. Heart and circulatory physiology ·

Human

Abstract summarized · Quality not appraised
Studied
An observational study examined relationships between testosterone, gender-minority stress and blood-pressure responses to brief physical and psychological stress.
Who / model
Twenty-four transgender or nonbinary adults assigned female at birth participated: 12 used testosterone and 12 did not.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
Found
Resting blood pressure was similar between groups. Greater minority stress was associated with a smaller response to psychological stress. Higher testosterone was associated with a larger diastolic response; its systolic association was less certain. These relationships were absent for resting pressure and cold-stress responses.
Limits
Study limitations were not stated in the abstract. Methodological quality has not been appraised.

Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary

Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1152/ajpheart.00548.2026

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