PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Selenium nanoparticles mitigated hepatic damage and genotoxicity, testicular and renal damage in rats intoxicated with aflatoxins.

Reproductive biology ·

Animal

Abstract summarized · Quality not appraised
Studied
An animal experiment tested whether selenium nanoparticles reduced liver, kidney and reproductive harm from aflatoxin.
Who / model
Thirty-six male rats aged three months were divided equally among control, selenium, aflatoxin and combined-exposure groups. Treatment duration is not stated.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
Found
Selenium-treated groups had higher testosterone and estradiol than the aflatoxin group. Tissue structure improved with combined treatment, but DNA fragmentation remained elevated with aflatoxin and combined exposure.
Limits
Tissue recovery was incomplete. Kidney toxicity did not return to normal; both selenium nanoparticles and aflatoxin had kidney-toxic effects.

Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary

Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1016/j.repbio.2026.101247

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