PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Longitudinal Changes in Competitive Performance in Elite 46,XY DSD Runners During Prolonged Testosterone Suppression.

Journal of applied physiology (Bethesda, Md. : 1985) ·

Study type unconfirmed

Abstract summarized · Quality not appraised
Studied
A retrospective longitudinal study examined official competitive performance during prolonged testosterone suppression in elite runners with androgen-sensitive differences of sex development.
Who / model
The study followed elite runners with type II 5α-reductase deficiency who maintained testosterone below the stated threshold after medical or surgical suppression.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
Found
Competitive performance declined during suppression, averaging 6.5% across observation and remaining about 6.0% after two years, with substantial individual variation.
Limits
The sample was small and performance responses varied substantially between athletes.

Read summary source ↗ · Prepared 9/16/2026 · AI-assisted, source-based summary

Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1152/japplphysiol.90031.2026

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