Mechanism of Kushen Tongguan Pill on benign prostatic hyperplasia: roles of TLR4/NF-κB pathway and macrophage M1 polarization.

Studied

A preclinical study tested Kushen Tongguan Pill in testosterone-propionate-induced benign prostatic hyperplasia and examined inflammatory signaling.

Who / model

The in vivo work used a rat BPH model induced by castration and testosterone propionate.

Studied dose & schedule

Dose and schedule have not yet been extracted for this summary.

Found

KSTG dose-dependently reduced prostate size measures and several inflammatory markers in the rat model.

Limits

Evidence was limited to animal and cell models, so the abstract does not demonstrate efficacy or safety in humans.

Read summary source ↗ · Prepared 9/16/2026 · AI-assisted, source-based summary