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SOURCE-LINKED STUDY SUMMARY

Effects of testosterone-augmented multimodal exercise intervention in spinal cord injury: a randomized controlled trial.

The Journal of clinical endocrinology and metabolism ·

Human

Abstract summarizedQuality not appraised
What was studied
A double-blind trial tested whether testosterone augments exercise rehabilitation after spinal cord injury.
Who / model studied
84 adults with spinal cord injury, including 76 men and 8 women.
Studied dose & schedule
Intramuscular testosterone undecanoate or placebo for 16 weeks; both groups received electrical-stimulation leg cycling and arm exercise. Dose was not specified in the abstract.
What the study found
Testosterone added 1.84 kg whole-body lean mass versus control (95% CI 0.52-3.16). The primary aerobic-capacity comparison was not significant. Adverse-event rates were similar.
Limitations & context
Abstract-based assessment. Lean mass is not synonymous with contractile muscle. Within-group fitness improvements do not establish superiority; rehabilitation findings cannot establish healthy-lifter benefits.

Read summary source ↗ · Prepared 10/15/2026 · AI-assisted, source-based summary

Review record & corrections

Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1210/clinem/dgag173

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