SOURCE-LINKED STUDY SUMMARY
Effects of Testosterone Treatment in Older Men.
Abstract summarizedQuality not appraised
- What was studied
- Three linked trials compared testosterone gel with placebo for one year, assessing sexual function, walking performance and vitality.
- Who / model studied
- 790 symptomatic men aged 65 or older had low testosterone concentrations.
- Studied dose & schedule
- Dose and schedule have not yet been extracted for this summary.
- What the study found
- Sexual activity, desire and erectile function improved. The main walking outcome did not improve in the Physical Function Trial, but a pooled analysis across all three trials favored testosterone. Vitality did not significantly improve; mood and depressive symptoms improved slightly. Adverse-event rates were similar.
- Limitations & context
- The authors stated that too few participants were enrolled to draw conclusions about treatment risks. The results concern older symptomatic men with low testosterone.
Read summary source ↗ · Prepared 9/22/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1056/nejmoa1506119