SOURCE-LINKED STUDY SUMMARY
A Randomized Prospective Double-Blind Comparison Trial of Clomiphene Citrate and Anastrozole in Raising Testosterone in Hypogonadal Infertile Men.
Abstract summarizedQuality not appraised
- What was studied
- This randomized double-blind trial compared clomiphene citrate with anastrozole for raising testosterone in hypogonadal infertile men.
- Who / model studied
- Twenty-six infertile men with testosterone below 350 ng/dL and normal luteinizing hormone were randomized.
- Studied dose & schedule
- Participants received clomiphene citrate 25 mg/day or anastrozole 1 mg/day for 12 weeks.
- What the study found
- Testosterone increased in both groups; reported values were 571 ng/dL with clomiphene and 408 ng/dL with anastrozole. Estradiol rose with clomiphene but fell with anastrozole.
- Limitations & context
- Abstract assessment: neither semen parameters nor patient-reported outcomes changed significantly. The abstract reports no adverse-event results, and this was a short, small trial.
Read summary source ↗ · Prepared 10/6/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1111/jsm.12944