SOURCE-LINKED STUDY SUMMARY
Adverse events associated with testosterone administration.
Abstract summarizedQuality not appraised
- What was studied
- Randomized trial comparing daily testosterone gel with placebo for 6 months, with adverse events and physical performance assessed.
- Who / model studied
- The trial enrolled 209 community-dwelling men aged at least 65 with mobility limitations and low testosterone; mean age was 74, with substantial chronic disease.
- Studied dose & schedule
- Dose and schedule have not yet been extracted for this summary.
- What the study found
- The trial stopped early after more cardiovascular-related adverse events with testosterone: 23 men versus 5 with placebo. Testosterone improved leg-press and chest-press strength and loaded stair climbing.
- Limitations & context
- The authors cautioned that the small trial and its medically complex, mobility-limited population prevent broad conclusions about testosterone safety.
Read summary source ↗ · Prepared 9/22/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1056/nejmoa1000485