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SOURCE-LINKED STUDY SUMMARY

The effects of growth hormone on body composition and physical performance in recreational athletes: a randomized trial.

Annals of internal medicine ·

Human

Abstract summarizedQuality not appraised
What was studied
A randomized, placebo-controlled trial tested growth hormone alone or with testosterone on body composition and physical performance in recreational athletes.
Who / model studied
Recreational athletes were studied in a blinded controlled experiment.
Studied dose & schedule
Eight weeks of assigned treatment followed by a six-week washout; growth hormone was tested alone and in combination with testosterone against placebo conditions.
What the study found
Growth hormone reduced fat mass and increased measured lean mass, with part of the lean-mass signal attributed to extracellular water and body cell mass. Sprint capacity improved, while broad strength and endurance effects were limited.
Limitations & context
The short trial and washout do not establish long-term performance benefit or safety. Findings from recreational athletes should not be generalized to growth-hormone deficiency treatment.

Read summary source ↗ · Prepared 9/25/2026 · AI-assisted, source-based summary

Review record & corrections

Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.7326/0003-4819-152-9-201005040-00007

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