SOURCE-LINKED STUDY SUMMARY
Comparison of the effects of high dose testosterone and 19-nortestosterone to a replacement dose of testosterone on strength and body composition in normal men.
Abstract summarizedQuality not appraised
- What was studied
- A double-blind comparison examined how androgen doses affected body composition and muscle strength in healthy men.
- Who / model studied
- Thirty healthy young men participated; biceps and quadriceps strength was measured before treatment and after the sixth injection.
- Studied dose & schedule
- Testosterone enanthate or 19-nortestosterone decanoate was given at 100 or 300 mg weekly for six weeks. Testosterone 100 mg weekly was the replacement-dose comparator.
- What the study found
- Weight was unchanged with testosterone 100 mg weekly; other groups gained about 3 kg. Estimated body fat did not change. Strength gains were small and variable, with only a trend favoring testosterone 300 mg weekly.
- Limitations & context
- The authors describe detectable changes beyond weight gain as highly variable and relatively small.
Read summary source ↗ · Prepared 9/24/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1016/0960-0760(91)90283-b