SOURCE-LINKED STUDY SUMMARY
Effects of oxandrolone on outcome measures in the severely burned: a multicenter prospective randomized double-blind trial.
Abstract summarizedQuality not appraised
- What was studied
- A multicenter randomized trial tested whether oxandrolone shortened hospitalization in adults with severe burns.
- Who / model studied
- The study enrolled 81 adults with burns covering 20%–60% of total body surface area.
- Studied dose & schedule
- Participants received oxandrolone 10 mg every 12 hours or placebo. Route and treatment duration were not reported in the abstract.
- What the study found
- Mean hospital stay was 31.6 days with oxandrolone versus 43.3 days with placebo. The abstract reports no detailed adverse-event counts and recommends monitoring hepatic transaminases.
- Limitations & context
- The trial stopped at roughly half its projected enrollment after a planned interim analysis. The severely burned, highly catabolic population does not establish effects in healthy athletes.
Read summary source ↗ · Prepared 10/6/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1097/01.bcr.0000202620.55751.4f