SOURCE-LINKED STUDY SUMMARY
Six-week improvements in muscle mass and strength during androgen therapy in older men.
Abstract summarizedQuality not appraised
- What was studied
- A randomized placebo-controlled study examined early changes in muscle mass, strength, leg power and physical function during oxandrolone treatment.
- Who / model studied
- Thirty-two older men, averaging 72 years of age, were assigned two-to-one to oxandrolone or placebo.
- Studied dose & schedule
- Oxandrolone 10 mg twice daily or matching placebo for 12 weeks; early outcomes were assessed at six weeks. Administration route was not stated.
- What the study found
- At six weeks, lean mass increased 2.7 kg with oxandrolone versus a 0.5 kg decline with placebo. Strength improved across four exercises. Leg muscle power and walking speed did not improve.
- Limitations & context
- Study limitations were not stated in the abstract. Methodological quality has not been appraised.
Read summary source ↗ · Prepared 9/24/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1093/gerona/60.12.1586