SOURCE-LINKED STUDY SUMMARY
Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression.
Abstract summarizedQuality not appraised
- What was studied
- A randomized trial tested whether hCG maintained testosterone inside the testes during suppression by injected testosterone.
- Who / model studied
- Twenty-nine men with normal reproductive physiology.
- Studied dose & schedule
- Testosterone enanthate 200 mg weekly plus placebo or hCG 125, 250 or 500 IU every other day for 3 weeks.
- What the study found
- Intratesticular testosterone fell 94% with testosterone plus placebo. With hCG, levels were 25% below baseline at 125 IU, 7% below at 250 IU and 26% above at 500 IU.
- Limitations & context
- Short study of a hormone marker, not demonstrated preservation of sperm production, pregnancy rates or long-term fertility.
Read summary source ↗ · Prepared 9/29/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1210/jc.2004-0802