SOURCE-LINKED STUDY SUMMARY
Treatment with oxandrolone and the durability of effects in older men.
What was studied?
A randomized trial examined oxandrolone’s effects on body composition, muscle size and strength in older men, including follow-up after treatment ended.
What changed?
The study measured lean mass, muscle size, fat and strength during treatment and then examined how much of the change remained after withdrawal.
Who was studied?
Healthy older men were assigned to oxandrolone or placebo; the accessible record describes a short controlled intervention and post-treatment follow-up.
Studied exposure
Oral oxandrolone 20 mg daily for 12 weeks, followed by observation after discontinuation, compared with placebo.
What remains uncertain?
The sample was small and the intervention and follow-up were short, so durability findings do not establish long-term benefit or safety in other populations.
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1152/japplphysiol.00808.2003