SOURCE-LINKED STUDY SUMMARY
Short-term oxandrolone administration stimulates net muscle protein synthesis in young men.
Abstract summarizedQuality not appraised
- What was studied
- A short before-and-after experiment measured muscle protein synthesis and breakdown during oxandrolone exposure.
- Who / model studied
- Six healthy young men were studied while fasting before and after treatment.
- Studied dose & schedule
- Oral oxandrolone 15 mg daily for 5 days; measurements were compared with each participant’s pretreatment values.
- What the study found
- Muscle fractional protein synthesis increased 44%, with no change in breakdown. Net balance improved but was not statistically different from zero. Androgen-receptor mRNA increased; IGF-I mRNA did not.
- Limitations & context
- A five-day experiment in six men cannot quantify long-term hypertrophy or establish safety. No separate placebo group is described in the abstract.
Read summary source ↗ · Prepared 9/25/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1210/jcem.84.8.5923