PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Muscle ultrastructure after strength training with placebo or anabolic steroid.

Canadian journal of applied physiology = Revue canadienne de physiologie appliquee ·

Human

What was studied?

A double-blind, counterbalanced study examined muscle-fibre size and small blood-vessel structure and supply during strength training with nandrolone or placebo.

What changed?

Fibre area increased significantly only within the steroid condition, but no measured outcome differed between steroid and placebo treatments. Capillary structure and supply did not change. The within-condition increase therefore did not demonstrate superiority over placebo.

Who was studied?

13 experienced male bodybuilders participated. Thigh-muscle biopsies before and after eight weeks assessed muscle-fibre and capillary characteristics.

Studied exposure

Weekly injections contained placebo or nandrolone decanoate, beginning with 200 mg and followed by 100 mg weekly over eight weeks. The abstract does not specify the injection route.

What remains uncertain?

Study limitations were not stated in the abstract. Methodological quality has not been appraised.

Abstract summarized · Quality not appraised

Review record & corrections

Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1139/h93-015

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