SOURCE-LINKED STUDY SUMMARY
Effects of resistance exercise training and nandrolone decanoate on body composition and muscle function among patients who receive hemodialysis: A randomized, controlled trial.
What was studied?
A randomized factorial trial tested nandrolone and resistance exercise. Primary outcomes were lean mass, thigh-muscle area, and knee-extension strength; physical performance and self-reported functioning were secondary.
What changed?
Nandrolone recipients gained 3.1 kg of lean mass; exercise alone did not significantly increase it. Both interventions increased thigh-muscle area additively. Exercise improved training-specific strength and self-reported functioning compared with nonexercising groups.
Who was studied?
79 maintenance-hemodialysis patients participated at university-affiliated dialysis units; sixty-eight completed the study.
Studied exposure
For 12 weeks, participants received blinded weekly nandrolone injections, 100 mg for women or 200 mg for men, or placebo, with or without lower-limb resistance training three times weekly during dialysis.
What remains uncertain?
Whether these interventions improve survival remains unresolved and requires further study. These findings concern dialysis patients, not healthy athletes.
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1681/asn.2006010034