SOURCE-LINKED STUDY SUMMARY
Effects of resistance exercise training and nandrolone decanoate on body composition and muscle function among patients who receive hemodialysis: A randomized, controlled trial.
Abstract summarizedQuality not appraised
- What was studied
- A randomized factorial trial tested nandrolone and resistance exercise. Primary outcomes were lean mass, thigh-muscle area, and knee-extension strength; physical performance and self-reported functioning were secondary.
- Who / model studied
- 79 maintenance-hemodialysis patients participated at university-affiliated dialysis units; sixty-eight completed the study.
- Studied dose & schedule
- For 12 weeks, participants received blinded weekly nandrolone injections, 100 mg for women or 200 mg for men, or placebo, with or without lower-limb resistance training three times weekly during dialysis.
- What the study found
- Nandrolone recipients gained 3.1 kg of lean mass; exercise alone did not significantly increase it. Both interventions increased thigh-muscle area additively. Exercise improved training-specific strength and self-reported functioning compared with nonexercising groups.
- Limitations & context
- Whether these interventions improve survival remains unresolved and requires further study. These findings concern dialysis patients, not healthy athletes.
Read summary source ↗ · Prepared 9/24/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1681/asn.2006010034