SOURCE-LINKED STUDY SUMMARY
Creatine supplementation effects on cognition, sleep, and menopause symptoms in response to six weeks of high-intensity resistance training in perimenopausal females.
Abstract summarizedQuality not appraised
- What was studied
- An exploratory randomized study tested creatine with resistance training for cognition, sleep and perimenopause symptoms.
- Who / model studied
- 51 perimenopausal women, average age 46, assigned to creatine, placebo or a nontraining control.
- Studied dose & schedule
- Oral creatine monohydrate 20 g/day for 5 days, then approximately 4.5 g/day for six weeks; creatine and placebo groups trained twice weekly.
- What the study found
- Sleep consistency at week 6 favored creatine by 7.4 percentage points versus placebo after baseline adjustment (p=0.015). Prefrontal oxygenation increased, but Stroop reaction-time improvement did not differ between groups.
- Limitations & context
- Abstract-based, short exploratory study using wearable and self-reported outcomes. Oxygenation is not proof of better thinking. Confidence intervals and adverse-event counts were unavailable. Publisher disclosures include supplement-industry and wearable-company ties.
Read summary source ↗ · Prepared 10/28/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1007/s00421-026-06481-6