PEDEvidence

SOURCE-LINKED STUDY SUMMARY

The Effect of Prior Creatine Intake for 28 Days on Accelerated Recovery from Exercise-Induced Muscle Damage: A Double-Blind, Randomized, Placebo-Controlled Trial.

Nutrients ·

Human

Full paper summarizedQuality not appraised
What was studied
A randomized trial tested whether four weeks of creatine monohydrate accelerated recovery from elbow-flexor damage induced by eccentric exercise.
Who / model studied
Twenty healthy Japanese men aged 21–36 years were randomized, with ten participants per group.
Studied dose & schedule
Participants consumed creatine monohydrate 3 g/day or microcrystalline-cellulose placebo for 28 days before a standardized eccentric dumbbell exercise.
What the study found
Creatine improved range of motion at 24 hours and maximal voluntary contraction at several time points through 168 hours, while reducing swelling, stiffness, and fatigue at selected time points. Soreness and urinary titin did not differ. No attributable adverse effects occurred.
Limitations & context
The study was small, included only young Japanese men, and measured short-term recovery after one laboratory muscle-damage protocol. It was partly industry funded.

Read summary source ↗ · Prepared 10/6/2026 · AI-assisted, source-based summary

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Summary prepared: . Source scope: full paper. This is an AI-assisted source summary, not an independent clinician sign-off.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.3390/nu16060896

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