SOURCE-LINKED STUDY SUMMARY
Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation.
Full paper summarizedQuality not appraised
- What was studied
- A double-blind crossover trial tested a single creatine dose during sleep deprivation, using cognitive tests and brain spectroscopy.
- Who / model studied
- Fifteen healthy adults aged 20–28, tested under creatine and placebo conditions.
- Studied dose & schedule
- One oral dose of creatine monohydrate, 0.35 g/kg, versus placebo on separate nights during 21 hours of wakefulness.
- What the study found
- Creatine improved word-memory performance and processing speed on several tasks versus placebo, alongside changes in brain energy metabolites. Effects were assessed over the same night.
- Limitations & context
- Small, acute sleep-deprivation experiment. It does not establish the same benefit in well-rested people or justify replacing sleep with creatine.
Read summary source ↗ · Prepared 9/29/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: full paper. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1038/s41598-024-54249-9