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SOURCE-LINKED STUDY SUMMARY

A 2-yr Randomized Controlled Trial on Creatine Supplementation during Exercise for Postmenopausal Bone Health.

Medicine and science in sports and exercise ·

Human

Full paper summarizedQuality not appraised
What was studied
A two-year randomized trial tested whether creatine added to resistance training and walking improved bone and physical outcomes in postmenopausal women.
Who / model studied
Two hundred thirty-seven postmenopausal women, mean age 59 years, were randomized.
Studied dose & schedule
Creatine monohydrate 0.14 g/kg/day or placebo accompanied resistance training three days weekly and walking six days weekly for two years.
What the study found
Creatine did not improve femoral-neck, total-hip or lumbar-spine BMD or 1-RM strength. Some femoral geometry measures and 80-m walking time favored creatine; lean-mass benefit appeared only in a completer subanalysis.
Limitations & context
Bone geometry is a surrogate, not fracture prevention. Both groups exercised, and the lean-mass result was a completer subanalysis. Kidney-related adverse events did not differ significantly between groups.

Read summary source ↗ · Prepared 10/6/2026 · AI-assisted, source-based summary

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Summary prepared: . Source scope: full paper. This is an AI-assisted source summary, not an independent clinician sign-off.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1249/mss.0000000000003202

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