Effects of human growth hormone in men over 60 years old.

Studied

A controlled study observed older men for six baseline months, then compared growth-hormone treatment with no treatment for six months.

Who / model

21 healthy men aged 61–81 with low IGF-I participated: 12 received growth hormone and nine received no treatment.

Studied dose & schedule

Dose and schedule have not yet been extracted for this summary.

Found

In treated men, lean mass increased 8.8 percent, fat mass decreased 14.4 percent and lumbar-spine bone density increased 1.6 percent. Forearm and upper-femur bone density did not significantly change. Skin thickness increased, but the reported result was not statistically significant. Untreated men had no significant changes in these measures.

Limits

No author-stated limitations or adverse-event results were available in the abstract. The comparator received no treatment; random allocation was not described.

Read summary source ↗ · Prepared 9/22/2026 · AI-assisted, source-based summary