SOURCE-LINKED STUDY SUMMARY
Outcomes of clomiphene citrate treatment in young hypogonadal men.
Abstract summarizedQuality not appraised
- What was studied
- This prospective case series assessed long-term hormonal and symptom outcomes during clomiphene treatment in younger men with hypogonadism.
- Who / model studied
- Eighty-six men, mean age 29, had two early-morning testosterone measurements below 300 ng/dL; 64% sought treatment for infertility.
- Studied dose & schedule
- Clomiphene began at 25 mg every other day and could increase to 50 mg every other day, targeting testosterone 550 ± 50 ng/dL; mean treatment duration was 19 months.
- What the study found
- Mean testosterone and gonadotropins rose significantly. More than half improved at least three ADAM symptoms; no major adverse effects were recorded.
- Limitations & context
- This was an uncontrolled, self-selected case series using a subjective questionnaire. It cannot establish comparative efficacy against testosterone therapy or placebo.
Read summary source ↗ · Prepared 10/6/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1111/j.1464-410x.2011.10702.x