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SOURCE-LINKED STUDY SUMMARY

Misuse of androgenic-anabolic steroids and human deltoid muscle fibers: differences between polydrug regimens and single drug administration.

European journal of applied physiology ·

Human

What was studied?

Two studies examined shoulder-muscle fibres in experienced male strength athletes: a double-blind nandrolone study and an observational comparison of self-selected steroid users with nonusers.

What changed?

Nandrolone showed no apparent effect on fibre size or type distribution. In self-selected users, mean fibre size increased 12.6%, with type I increasing 10.8% and type II 14.6%; fibre-type distribution was unchanged. This observational comparison cannot isolate individual drugs' effects.

Who was studied?

The nandrolone study involved 15 volunteers. Separately, 12 men self-administered various steroids and seven nonusers served as controls. Biopsies were taken before and after eight weeks.

Studied exposure

Nandrolone decanoate was administered intramuscularly at 200 mg/week for eight weeks. The self-administered regimens used multiple steroids at supratherapeutic doses; exact amounts were not supplied.

What remains uncertain?

Study limitations were not stated in the abstract. Methodological quality has not been appraised.

Abstract summarized · Quality not appraised

Review record & corrections

Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1007/s00421-001-0535-7

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