PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Anabolic effects of nandrolone decanoate in patients receiving dialysis: a randomized controlled trial.

JAMA ·

Human

What was studied?

A randomized controlled trial examined nandrolone’s anabolic effects in patients receiving dialysis.

What changed?

The study assessed whether nandrolone increased lean body mass and improved strength, walking, stair-climbing or related function compared with placebo.

Who was studied?

Adults receiving chronic dialysis were studied with body-composition, functional and quality-of-life outcomes.

Studied exposure

Nandrolone decanoate 100 mg weekly or placebo for 6 months, alongside usual dialysis care.

What remains uncertain?

Dialysis patients have a distinct disease burden and treatment context. The trial was not designed to establish long-term safety or effects in healthy people.

Abstract summarized · Quality not appraised

Review record & corrections

Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1001/jama.281.14.1275

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