PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Effects of pharmacological doses of nandrolone decanoate and progressive resistance training in immunodeficient patients infected with human immunodeficiency virus.

The Journal of clinical endocrinology and metabolism ·

Human

Abstract summarized · Quality not appraised
Studied
An open-label randomized study compared nandrolone alone with nandrolone plus supervised resistance training for 12 weeks.
Who / model
Thirty men with HIV and reduced immune-cell counts participated. There was no placebo group.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
Found
Lean mass increased 3.9 kg with nandrolone alone and 5.2 kg with added training. Strength gains were greater with training. Body-cell mass and measured thigh-muscle areas increased in both groups without significant between-group differences for those measures.
Limits
The study was explicitly open-label and lacked a placebo comparison, limiting attribution of within-group changes to nandrolone. The abstract does not report adverse-event results; these findings do not establish safety.

Read summary source ↗ · Prepared 9/22/2026 · AI-assisted, source-based summary

Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1210/jcem.84.4.5610

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