Human
Do mitochondrial effects translate into human performance?
Demonstrated findings
A randomized trial in older adults found improvements in muscle-endurance measures; between-group differences in the primary walking-distance and ATP-production endpoints were not significant.
What might this mean? · interpretation
Some functional signals are encouraging, with mixed results across endpoints.
What might this mean, and what would change the interpretation?
A selective positive endpoint cannot stand in for success across all outcomes or populations.
What would clarify this: Independent replication with prespecified functional endpoints.