Human
Do mitochondrial effects translate into human performance?
Demonstrated findings
A randomized trial in older adults found improvements in muscle-endurance measures; between-group differences in the primary walking-distance and ATP-production endpoints were not significant.
What might this mean? ยท interpretation
Some functional signals are encouraging, with mixed results across endpoints.
What might this mean, and what would change the interpretation?
A selective positive endpoint cannot stand in for success across all outcomes or populations.
What would clarify this: Independent replication with prespecified functional endpoints.