Human
Does increased lean mass also mean better strength?
65 adults aged 60–81; randomized, placebo-controlled study.
Demonstrated findings
A randomized trial in older adults increased GH, IGF-1 and fat-free mass, without improving strength or physical function.
What might this mean? · interpretation
Hormonal and body-composition changes can occur without a demonstrated functional improvement.
What might this mean, and what would change the interpretation?
Older adults differ from young trained athletes; appetite, edema and glucose-related effects matter to interpretation.
What would clarify this: Trials measuring muscle function and composition in the population of interest.