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SOURCE-LINKED STUDY SUMMARY

"Anabolic" effects of methandienone in men undergoing athletic training.

Lancet (London, England) ·

Human

Abstract summarizedQuality not appraised
What was studied
A double-blind crossover experiment examined whether methandienone (Dianabol) changed body composition, strength, performance and endocrine function during weight training.
Who / model studied
The study involved 11 athletic men undertaking a course of weight training.
Studied dose & schedule
Methandienone was given at 100 mg/day for 6 weeks, with a placebo period for comparison. The abstract does not specify administration route.
What the study found
Body weight, lean mass and muscle size increased with methandienone. Strength and performance improved during both training periods, without a significant drug–placebo difference. Plasma testosterone decreased, while plasma cortisol and urinary cortisol excretion increased.
Limitations & context
The authors could not establish whether the body-composition changes reflected an anabolic effect or increased intracellular fluid.

Read summary source ↗ · Prepared 9/24/2026 · AI-assisted, source-based summary

Review record & corrections

Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1016/s0140-6736(76)90001-5

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