SOURCE-LINKED STUDY SUMMARY
Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study.
Abstract summarizedQuality not appraised
- What was studied
- Tested whether daily nicotinamide mononucleotide changes blood NAD, physical function, sleep and stress in older adults.
- Who / model studied
- Sixty older adults were randomized to NMN or placebo in a double-blind parallel-group trial.
- Studied dose & schedule
- The NMN group consumed 250 mg/day orally for 12 weeks; the comparator was placebo.
- What the study found
- The primary stepping test did not differ. Secondary analyses favored NMN for 4-m walking time and blood NAD metabolites after 12 weeks.
- Limitations & context
- Walking and sleep findings were secondary to the negative primary stepping result. The sample and follow-up were limited, although no test-substance adverse effects were observed.
Read summary source ↗ · Prepared 10/6/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1007/s11357-024-01204-1