SOURCE-LINKED STUDY SUMMARY
Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study.
Full paper summarizedQuality not appraised
- What was studied
- Tested whether adding nicotinamide mononucleotide to a standardized exercise program improves aerobic capacity in recreationally trained runners.
- Who / model studied
- Forty-eight young and middle-aged recreational runners entered a randomized, double-blind, placebo-controlled four-arm trial.
- Studied dose & schedule
- For 6 weeks, participants took 300, 600 or 1200 mg/day NMN or placebo while training 5–6 times weekly.
- What the study found
- Medium and high doses improved oxygen uptake and power at ventilatory thresholds more than placebo. Maximal oxygen uptake, oxygen pulse, peak power and body composition did not improve.
- Limitations & context
- This small, six-week trial involved trained runners. It improved submaximal thresholds but did not increase maximal oxygen uptake or peak power, limiting generalizability.
Read summary source ↗ · Prepared 10/6/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: full paper. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1186/s12970-021-00442-4