PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Liraglutide and Renal Outcomes in Type 2 Diabetes.

The New England journal of medicine ·

Human

Abstract summarized · Quality not appraised
Studied
This prespecified secondary analysis of the randomized LEADER trial compared liraglutide with placebo, added to usual care, for a composite kidney outcome.
Who / model
The trial randomized 9340 people and followed them for a median 3.84 years.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
Found
The kidney outcome occurred in 268 of 4668 liraglutide recipients versus 337 of 4672 placebo recipients. The difference was driven mainly by less new persistent macroalbuminuria.
Limits
The kidney outcome was a secondary composite outcome. The abstract does not provide a formal methodological quality appraisal.

Read summary source ↗ · Prepared 9/22/2026 · AI-assisted, source-based summary

Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1056/nejmoa1616011

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