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SOURCE-LINKED STUDY SUMMARY

Liraglutide and Renal Outcomes in Type 2 Diabetes.

The New England journal of medicine ·

Human

Abstract summarizedQuality not appraised
What was studied
This prespecified secondary analysis of the randomized LEADER trial compared liraglutide with placebo, added to usual care, for a composite kidney outcome.
Who / model studied
The trial randomized 9340 people and followed them for a median 3.84 years.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
What the study found
The kidney outcome occurred in 268 of 4668 liraglutide recipients versus 337 of 4672 placebo recipients. The difference was driven mainly by less new persistent macroalbuminuria.
Limitations & context
The kidney outcome was a secondary composite outcome. The abstract does not provide a formal methodological quality appraisal.

Read summary source ↗ · Prepared 9/22/2026 · AI-assisted, source-based summary

Review record & corrections

Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1056/nejmoa1616011

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