SOURCE-LINKED STUDY SUMMARY
Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined.
Abstract summarizedQuality not appraised
- What was studied
- This randomized, placebo-controlled trial compared exercise, liraglutide, their combination, and placebo for one year after an eight-week low-calorie diet.
- Who / model studied
- The study included 195 adults with obesity and no diabetes who had already lost an average 13.1 kg during the diet phase.
- Studied dose & schedule
- Dose and schedule have not yet been extracted for this summary.
- What the study found
- Compared with placebo, weight was lower by 4.1 kg with exercise, 6.8 kg with liraglutide, and 9.5 kg with both. Increased heart rate and gallstones occurred more often with liraglutide alone than with the combination.
- Limitations & context
- The combination was not significantly better than liraglutide alone for weight loss, and results apply to post-diet adults without diabetes over one year.
Read summary source ↗ · Prepared 9/22/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1056/nejmoa2028198