PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis.

The American journal of clinical nutrition ·

Human

Abstract summarizedQuality not appraised
What was studied
A randomized double-blind crossover study tested vitamin C-enriched gelatin around brief exercise as a stimulus for collagen synthesis.
Who / model studied
Eight healthy, recreationally active young men completed all placebo, 5-g and 15-g gelatin conditions.
Studied dose & schedule
Participants consumed placebo, 5 g or 15 g vitamin C-enriched gelatin one hour before six minutes of rope-skipping, three times daily for three days.
What the study found
The 15-g condition doubled circulating PINP, a collagen-synthesis marker; serum collected after gelatin also increased collagen content and mechanics in engineered ligaments.
Limitations & context
The human sample was tiny and outcomes were biomarkers plus an engineered-ligament assay, not injury healing, pain, reinjury, or return to sport.

Read summary source ↗ · Prepared 10/6/2026 · AI-assisted, source-based summary

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Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.3945/ajcn.116.138594

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