PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression.

Biological & pharmaceutical bulletin ·

Cell / tissue

Abstract summarized · Quality not appraised
Studied
The study examined how YK-11 affects muscle-cell development and follistatin, a protein involved in muscle biology.
Who / model
C2C12 muscle precursor cells were studied.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
Found
YK-11 increased follistatin and muscle-development markers. Blocking follistatin reversed the effect on cell development.
Limits
These are cell findings; this experiment does not establish muscle growth or safety in people.

Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary

Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1248/bpb.b13-00231

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