PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Thymosin beta4 accelerates wound healing.

The Journal of investigative dermatology ·

Animal · Cell / tissue

Abstract summarized · Quality not appraised
Studied
Research compared thymosin beta-4 with saline in a rat skin-wound model, alongside laboratory tests of skin-cell migration.
Who / model
Rats had full-thickness wounds assessed at four and seven days. Cell migration was measured after 4–5 hours. Sample sizes were not stated in the abstract.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
Found
Treated wounds showed 42% greater surface re-covering at four days and up to 61% at seven days. Wound contraction was at least 11% greater by day seven, with increased collagen deposition and blood-vessel formation. Skin-cell migration increased two- to threefold versus culture medium alone.
Limits
No author-stated limitations or adverse-event results were available in the abstract. Rat and cell findings do not establish human wound-healing effectiveness.

Read summary source ↗ · Prepared 9/22/2026 · AI-assisted, source-based summary

Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1046/j.1523-1747.1999.00708.x

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