Weight loss with a lower dose compounded semaglutide and behavioral weight management program: A real-world matched retrospective cohort study

Studied

A 16-week retrospective study compared a behavioural weight-management programme alone with programmes including lower or higher amounts of compounded semaglutide.

Who / model

The full sample included 29,788 users, mostly middle-aged women. The matched analysis included 3,657 users, with 1,219 per group.

Studied dose & schedule

Dose and schedule have not yet been extracted for this summary.

Found

In the matched groups, average weight loss was 2.6% with the behavioural programme alone, 8.3% with lower-dose compounded semaglutide and 9.1% with the higher-dose programme. These observational comparisons do not isolate the effect of dose.

Limits

Study limitations were not stated in the abstract. Methodological quality has not been appraised.

Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary