PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Preventing Weight Regain After Glucagon-Like Peptide‑1 Therapy Discontinuation: A Pilot Randomized Controlled Trial.

Obesity science & practice ·

Human

Full paper summarizedQuality not appraised
What was studied
A randomized pilot tested behavioral-app support or medically tailored meals versus usual care after GLP-1 treatment stopped.
Who / model studied
39 adults with prior GLP-1-associated weight loss; 34 completed a final weigh-in.
Studied dose & schedule
Four months of a Noom subscription, 10 tailored meals weekly, or provider-directed usual care.
What the study found
Estimated weight gain was 10.75% with usual care, 3.60% with the app and 3.58% with meals. Adherence, satisfaction, diet quality and perceived health did not significantly differ. No harms were reported.
Limitations & context
Weight was exploratory; the small pilot was not powered for definitive efficacy. Follow-up was short and usual care varied. All groups regained weight, and results do not establish durable maintenance.

Read summary source ↗ · Prepared 10/15/2026 · AI-assisted, source-based summary

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Summary prepared: . Source scope: full paper. This is an AI-assisted source summary, not an independent clinician sign-off.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1002/osp4.70194

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