SOURCE-LINKED STUDY SUMMARY
Effects of lemborexant vs placebo on total daytime sleep in shift workers: a randomized controlled trial.
Abstract summarizedQuality not appraised
- What was studied
- A pilot trial tested an orexin blocker for daytime sleep in shift workers.
- Who / model studied
- 29 night-shift workers, including 28 women.
- Studied dose & schedule
- One week at 5 mg, then two weeks at 5 or 10 mg lemborexant, versus placebo.
- What the study found
- No significant placebo advantage for sleep duration, efficiency, quality or insomnia severity. Exploratory higher-dose findings did not beat placebo. No serious adverse events occurred in the active group.
- Limitations & context
- Small, short trial; absence of significance is not proof of equivalence. Dose groups were not independently randomized comparisons. Abstract assessment only.
Read summary source ↗ · Prepared 10/15/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1007/s44470-026-00199-0