Improvement of small fiber neuropathy assessed by corneal confocal microscopy following semaglutide treatment: a case report and literature review.

Studied

Changes in small nerve fibers and neuropathy measurements after semaglutide treatment.

Who / model

One 57-year-old man with type 2 diabetes, obesity and peripheral neuropathy, followed for 6 months. Corneal microscopy assessed small nerve fibers.

Studied dose & schedule

Dose and schedule have not yet been extracted for this summary.

Found

Body mass index and average blood sugar improved, and corneal nerve measurements improved. Neuropathy symptom scores, disability scores and vibration perception did not change.

Limits

A single case cannot establish neuropathy reversal or distinguish a direct drug effect from improved metabolism. The unchanged symptoms are an important limit.

Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary