PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Carbon Emission Impact of Semaglutide in People with Obesity in the UK Using a Disease Modelling Approach.

PharmacoEconomics ·

Computer model

Abstract summarized · Quality not appraised
Studied
A lifetime disease model compared semaglutide plus diet and exercise with diet and exercise alone, estimating health outcomes and carbon emissions.
Who / model
The model used STEP and SELECT trial data for UK populations with overweight or obesity, including groups with complications or established cardiovascular disease. No new participant sample is described.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
Found
Estimated lifetime emissions fell 1.8% and 1.9% in two populations. In established cardiovascular disease, estimated survival rose 0.56 years, but emissions increased from 14,444 to 14,700 kilograms of carbon-dioxide equivalent. These are modelled projections.
Limits
Study limitations were not stated in the abstract. Methodological quality has not been appraised.

Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary

Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1007/s40273-026-01659-4

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