SOURCE-LINKED STUDY SUMMARY
Increased Energy Expenditure through Intermittent Cold Exposure Does Not Enhance Tirzepatide Induced Weight-loss in Obese Mice.
Abstract summarizedQuality not appraised
- What was studied
- An experiment tested whether intermittent cold exposure added to tirzepatide's effects on weight and blood-sugar regulation.
- Who / model studied
- Male and female mice received a high-fat diet for eight weeks, then tirzepatide or vehicle, with or without cold exposure, for three weeks. The abstract does not state the number of mice.
- Studied dose & schedule
- Dose and schedule have not yet been extracted for this summary.
- What the study found
- Tirzepatide reduced weight, food intake and body fat in both sexes. Cold exposure briefly increased energy use and improved blood-sugar regulation without weight changes. Combining them produced no additional effects.
- Limitations & context
- Study limitations were not stated in the abstract. Methodological quality has not been appraised.
Read summary source ↗ · Prepared 9/15/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1152/ajpregu.00220.2026