SOURCE-LINKED STUDY SUMMARY
Combined creatine and HMB co-supplementation improves functional strength independent of muscle mass in physically active older adults: a randomized crossover trial.
Full paper summarizedQuality not appraised
- What was studied
- A double-blind crossover trial tested combined creatine/HMB alongside supervised exercise.
- Who / model studied
- 30 physically active adults aged at least 60 years.
- Studied dose & schedule
- Daily oral creatine 3 g plus HMB 3 g versus inulin placebo; two six-week periods separated by a three-week washout, with exercise in both.
- What the study found
- Functional strength and endurance improved. Body-composition interactions favored supplementation, but within-condition mass changes were not significant, so this is not clear evidence of hypertrophy.
- Limitations & context
- Bioimpedance estimates, small sample and short follow-up limit interpretation. No separate creatine or HMB arms established synergy. Selected full-paper methods, results and limitations checked.
Read summary source ↗ · Prepared 10/15/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: full paper. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1007/s11357-025-01889-y