PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide.

JAMA ophthalmology ·

Human

Abstract summarized · Quality not appraised
Studied
A retrospective matched cohort assessed whether prescribed semaglutide was associated with nonarteritic anterior ischemic optic neuropathy.
Who / model
Patients evaluated by neuro-ophthalmologists at one academic institution were analyzed separately for type 2 diabetes and overweight or obesity.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
Found
Semaglutide prescriptions were associated with higher NAION risk in both clinical groups compared with non-GLP-1 medications.
Limits
The observational single-institution design cannot establish causality, and the authors called for further study.

Read summary source ↗ · Prepared 9/16/2026 · AI-assisted, source-based summary

Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1001/jamaophthalmol.2024.2296

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