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SOURCE-LINKED STUDY SUMMARY

Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide.

JAMA ophthalmology ·

Human

Abstract summarizedQuality not appraised
What was studied
A retrospective matched cohort assessed whether prescribed semaglutide was associated with nonarteritic anterior ischemic optic neuropathy.
Who / model studied
Patients evaluated by neuro-ophthalmologists at one academic institution were analyzed separately for type 2 diabetes and overweight or obesity.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
What the study found
Semaglutide prescriptions were associated with higher NAION risk in both clinical groups compared with non-GLP-1 medications.
Limitations & context
The observational single-institution design cannot establish causality, and the authors called for further study.

Read summary source ↗ · Prepared 9/16/2026 · AI-assisted, source-based summary

Review record & corrections

Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1001/jamaophthalmol.2024.2296

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